Motilant Tablet (Domperidone 10 mg)

Motilant tablet contains domperidone, a dopamine receptor antagonist that works by enhancing gastrointestinal motility. It is primarily used to relieve symptoms of nausea, vomiting, and discomfort caused by delayed gastric emptying or other gastrointestinal motility disorders.

Mechanism of Action

Domperidone acts by blocking dopamine (D2) receptors in the upper gastrointestinal tract. This blockage increases the movement of the stomach and intestines, facilitating faster gastric emptying and reducing feelings of nausea and bloating.

Indications

• Relief of nausea and vomiting caused by delayed gastric emptying

• Treatment of gastroparesis (delayed stomach emptying)

• Management of symptoms related to gastrointestinal motility disorders such as bloating, fullness, and heartburn

• Alleviating nausea caused by medication side effects (e.g., chemotherapy)

Dosage and Administration

Motilant is usually taken orally, often 10 mg three times daily before meals. However, the exact dosage and duration should be determined by a healthcare professional based on individual patient needs.

Side Effects

Common side effects may include:

• Headache

• Dry mouth

• Abdominal cramps

• Dizziness

Serious side effects are rare but may include allergic reactions or cardiac issues, especially with higher doses or prolonged use.

Precautions

• Not recommended for use in children under 12 years of age

• Patients with liver or kidney impairment should use with caution

• Avoid alcohol during treatment

• Consult a doctor if pregnant or breastfeeding before use

Drug Interactions

Motilant may interact with medications such as certain antifungals, antibiotics, and other drugs that affect heart rhythm. Always inform your healthcare provider about all medicines you are taking.

Storage

Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.