Aceclora 100 mg Tablet (Aceclofenac)

Aceclora 100 mg contains aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID) widely used to relieve pain and inflammation. It is primarily prescribed for the management of musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as for acute pain syndromes like soft tissue injuries.

Mechanism of Action

Aceclofenac works by inhibiting the enzyme cyclooxygenase (COX), particularly COX-2, which is involved in the production of prostaglandins—chemical mediators that cause inflammation, pain, and swelling. By reducing prostaglandin synthesis, Aceclora effectively decreases inflammation and provides analgesic (pain-relieving) effects.

Indications

• Osteoarthritis: Relieves joint pain, stiffness, and inflammation

• Rheumatoid arthritis: Helps control inflammation and joint damage

• Ankylosing spondylitis: Reduces spinal inflammation and improves mobility

• Soft tissue injuries: Manages pain and swelling from sprains, strains, or trauma

• Postoperative pain: Sometimes prescribed to reduce inflammation after surgery

Dosage and Administration

The usual dose of Aceclora 100 mg is one tablet twice daily, taken orally with meals to reduce the risk of gastrointestinal irritation. The exact dose and duration depend on the severity of the condition and the patient’s response. It should be taken under medical supervision, especially for long-term use.

Side Effects

Common side effects include:

• Gastrointestinal discomfort such as nausea, indigestion, and abdominal pain

• Dizziness or headache

• Skin rash or itching (rare)

• Edema or fluid retention (in some cases)

Serious but rare adverse effects:

• Gastrointestinal bleeding or ulcers

• Liver or kidney dysfunction

• Cardiovascular issues such as hypertension or increased risk of heart attack/stroke with prolonged use

Precautions

• Avoid use in patients with known hypersensitivity to aceclofenac or other NSAIDs

• Use cautiously in individuals with history of gastrointestinal ulcers, bleeding, or cardiovascular diseases

• Not recommended during the third trimester of pregnancy or breastfeeding without doctor’s advice

• Monitor kidney and liver function during prolonged therapy

• Avoid concurrent use with other NSAIDs or anticoagulants unless prescribed by a physician

Drug Interactions

Aceclora may interact with:

• Blood thinners (e.g., warfarin) increasing bleeding risk

• Other NSAIDs or corticosteroids increasing gastrointestinal side effects

• Antihypertensive drugs reducing their effectiveness

• Lithium or methotrexate requiring monitoring

Storage

Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.

Aceclora 100 mg is a potent NSAID effective in managing pain and inflammation in a range of musculoskeletal and inflammatory conditions. Proper medical guidance is essential to minimize side effects and ensure safe use.