Prikast 10 mg — Detailed Product Description

Generic Name: Montelukast Sodium
Brand Name: Prikast 10 mg
Manufacturer: Pristine Pharmaceuticals Ltd.
Dosage Form: Oral Tablet
Strength: 10 mg
Drug Class: Leukotriene Receptor Antagonist (LTRA)

💊 Overview

Prikast 10 mg is a prescription medication that contains Montelukast Sodium, a leukotriene receptor antagonist used primarily for the treatment and management of asthma, allergic rhinitis, and exercise-induced bronchospasm. It is especially effective in preventing symptoms caused by allergens, environmental triggers, or exercise by blocking the action of leukotrienes—chemical substances in the body that contribute to inflammation, bronchoconstriction, and mucus production.

✅ Indications

Prikast 10 mg is used in the management and prevention of:

• Chronic asthma in adults and adolescents (≥15 years)

• Seasonal allergic rhinitis (hay fever)

• Perennial allergic rhinitis

• Exercise-induced bronchoconstriction

• Night-time asthma symptoms

• Environmental allergy symptoms

⚙️ Mechanism of Action

Montelukast selectively blocks cysteinyl leukotriene (CysLT1) receptors found in the airways and on other pro-inflammatory cells. These leukotrienes are released during allergic reactions and asthma attacks, leading to airway swelling, constriction, and mucus buildup.

By antagonizing these receptors, Prikast reduces:

• Bronchial inflammation

• Airway hyperresponsiveness

• Mucus secretion

• Nasal congestion and sneezing

🧪 Dosage and Administration

• Standard Adult Dosage:
  One tablet (10 mg) taken orally once daily in the evening.

• Route: Oral

• With or Without Food: Can be taken regardless of meals

• Special Populations: Use with caution in patients with hepatic impairment; no dose adjustment needed for renal impairment

⚠️ Always follow your physician’s prescribed dosage and instructions.

🛑 Contraindications

• Hypersensitivity to Montelukast or any inactive ingredients in the formulation

• Not indicated for the relief of acute asthma attacks

⚠️ Warnings and Precautions

• Neuropsychiatric Events: Reports of agitation, aggression, depression, and suicidal thoughts (rare but serious)

• Asthma Control: Not a replacement for inhaled or oral corticosteroids in patients with asthma

• Churg-Strauss Syndrome: Rare cases reported, particularly when corticosteroids are withdrawn

🔄 Drug Interactions

• No significant drug interactions with theophylline, prednisone, oral contraceptives, or digoxin

• May be metabolized by CYP3A4 and CYP2C9 enzymes – caution with strong inducers/inhibitors

📉 Side Effects

Common (≥1%):

• Headache

• Abdominal pain

• Cough

• Fatigue

• Fever

Rare but serious:

• Mood changes or behavioral disturbances

• Tremors or seizures

• Liver enzyme abnormalities

• Anaphylaxis or rash

Patients should report any changes in mood or behavior to a healthcare provider immediately.

🔒 Storage Instructions

• Store below 25°C

• Keep in original packaging to protect from light and moisture

• Keep out of reach of children

📦 Packaging

Typically available in:

• Blister packs of 10 tablets

• Box of 10x10 tablets (100 tablets)